Kits and reagents for NGS sequencing

Macedonian Academy of Sciences and Arts

Рок

Рокот за прием на понудите беше 2022-09-23. Набавката беше објавена на 2022-08-24.

Кој?

• Macedonian Academy of Sciences and Arts

Што?

• Медицинска опрема, фармацевтски производи и производи за лична нега

Каде?

• Северна Македонија › Северна Македонија

Историја на набавките

Датум	Документ
2022-08-24	Оглас за договор

Оглас за договор (2022-08-24)
Предмет
Опсег на набавката
Наслов: Medical equipments, pharmaceuticals and personal care products
Референтен број: 14107/2022
Краток опис: Kits and reagents for NGS sequencing
Метаподатоци на огласот
Оригинален јазик: англиски 🗣️
Вид на документ: Оглас за договор
Природа на договорот: Стоки
Регулатива: Друго
Заеднички речник на набавки (CPV)
Шифра: Медицинска опрема, фармацевтски производи и производи за лична нега 📦
Дополнителен CPV: Медицинска опрема, фармацевтски производи и производи за лична нега 📦
Место на извршување
NUTS регион: Северна Македонија 🏙️

Постапка
Вид на постапка: Отворена постапка
Вид на понуда: Поднесување за сите делови
Критериуми за доделување
Најниска цена

Договорен орган
Идентитет
Земја: Северна Македонија 🇲🇰
Вид на органот кој доделува: Министерство или кој било друг национален или федерален орган
Име на органот кој доделува: Macedonian Academy of Sciences and Arts
Поштенска адреса: bul. Krste Misirkov br. 2
Поштенски број: 1000
Поштенско место: Skopje
Контакт
Интернет-адреса: http://manu.edu.mk/ 🌏
Е-пошта: emilija@manu.edu.mk 📧
URL за документи: https://www.e-nabavki.gov.mk/PublicAccess/home.aspx#/dossie/bd3fc7ce-f8fc-452d-8dfe-309359709971/1 🌏

Референца
Датуми
Датум на испраќање: 2022-08-24 📅
Рок за поднесување: 2022-09-23 📅
Датум на објавување: 2022-08-29 📅
Идентификатори
Број на огласот: 2022/S 165-470179
OJ-S издание: 165

Предмет
Опсег на набавката
Проценета вкупна вредност: 15 000 000 MKD 💰
Наслов на делот: Sequencing panel through specialized oligo-target regions of interest, which includes a minimum of 94 target genes and 284 SNPs associated with cancer predisposition. Panel to include kit of reagents,
Број на дел: 1
Краток опис:

Sequencing panel through specialized oligo-target regions of interest, which includes a minimum of 94 target genes and 284 SNPs associated with cancer predisposition. Panel to include kit of reagents, library and sequencing cartridges for 96 samples with included cartridges for a minimum of 4 analyzes of 24 samples at a time compatible with Illumina MiSeq sequencer, or equivalent

Времетраење: 12 месеци
Наслов на делот: A pre-designed and ready-to-use panel for sequencing through specialized oligo-target regions of interest, including a minimum of 94 target genes and 284 SNPs with 4000 probes of interest associated w
Број на дел: 2
Краток опис:

A pre-designed and ready-to-use panel for sequencing through specialized oligo-target regions of interest, including a minimum of 94 target genes and 284 SNPs with 4000 probes of interest associated with a predisposition to cancers, sufficient for 8 enrichment reactions and 96 samples, compatible for MiSeq sequencer IIllumina or equivalent. TruSight Cancer Gene Set or equivalent

Наслов на делот: 96 dual indexes of size 10 nucleotide bases each with pre-prepared combinations of the i5 and i7 ends, pre-prepared on a 96-position board and ready to use. Each well on the plate should have a unique
Број на дел: 3
Краток опис:

96 dual indexes of size 10 nucleotide bases each with pre-prepared combinations of the i5 and i7 ends, pre-prepared on a 96-position board and ready to use. Each well on the plate should have a unique combination. It must be compatible with part 3.

Наслов на делот: A kit for preparation of a target-sequencing library of samples by tagmentation for DNA fragmentation and adapter addition. This kit should allow the preparation of enrichment-based sequencing of 96 s
Број на дел: 4
Краток опис:

A kit for preparation of a target-sequencing library of samples by tagmentation for DNA fragmentation and adapter addition. This kit should allow the preparation of enrichment-based sequencing of 96 samples. This kit is suitable for the MiSeq personal sequencer and compatible with the offered parts 2,3 and 5. Ilumina DNA Prep enrichment panel or equivalent.

Наслов на делот: A ready-to-use cartridge with a capacity of 300 cycles, compatible with Illumina sequencing panels on the MiSeq personal sequencer. MiSeq Reagent Kit V2 (300 cycles), or equivalent
Број на дел: 5
Краток опис:

A ready-to-use cartridge with a capacity of 300 cycles, compatible with Illumina sequencing panels on the MiSeq personal sequencer. MiSeq Reagent Kit V2 (300 cycles), or equivalent

Наслов на делот: Ready-to-use cartridge with a capacity of 300 cycles, compatible with Illumina sequencing panels on the MiSeq personal sequencer, capable of 4 million reads per cell MiSeq Reagent mikro Kit V2 (300 cy
Број на дел: 6
Краток опис:

Ready-to-use cartridge with a capacity of 300 cycles, compatible with Illumina sequencing panels on the MiSeq personal sequencer, capable of 4 million reads per cell MiSeq Reagent mikro Kit V2 (300 cycles), or equivalent

Наслов на делот: A ready-to-use 300-cycle capacity cartridge compatible with Illumina sequencing panels on the NextSeq550dx personal sequencer or equivalent capable of reading up to 400 million fragments in parallel p
Број на дел: 7
Краток опис:

A ready-to-use 300-cycle capacity cartridge compatible with Illumina sequencing panels on the NextSeq550dx personal sequencer or equivalent capable of reading up to 400 million fragments in parallel per cell. NextSeq 500/550 High Output Kit v2.5 (300 Cycles), or equivalent.

Наслов на делот: A ready-to-use 300-cycle capacity cartridge compatible with Illumina sequencing panels on the NextSeq550dx personal sequencer or equivalent capable of reading up to 130 million fragments in parallel p
Број на дел: 8
Краток опис:

A ready-to-use 300-cycle capacity cartridge compatible with Illumina sequencing panels on the NextSeq550dx personal sequencer or equivalent capable of reading up to 130 million fragments in parallel per cell. NextSeq 500/550 Mid Output Kit v2.5 (300 Cycles), or equivalent.

Наслов на делот: A kit for preparation of a target-sequencing library of samples by tagmentation for DNA fragmentation and adapter addition. This kit should enable the preparation of enrichment-based sequencing suffic
Број на дел: 9
Краток опис:

A kit for preparation of a target-sequencing library of samples by tagmentation for DNA fragmentation and adapter addition. This kit should enable the preparation of enrichment-based sequencing sufficient for 8 enrichment reactions of 12 samples each, that is, for a total of 96 samples. This kit is suitable for the NextSeq550dx personal sequencer or equivalent and compatible with the offered parts 8,10,11 and 13. Ilumina DNA Prep enrichment kit, or equivalent.

Наслов на делот: A panel of oligonucleotide probes for enrichment of nucleotide sequences of interest. The samples are intended for sequencing of the complete human exome (Whole Exome Sequencing, WES). This kit is com
Број на дел: 10
Краток опис:

A panel of oligonucleotide probes for enrichment of nucleotide sequences of interest. The samples are intended for sequencing of the complete human exome (Whole Exome Sequencing, WES). This kit is compatible with the Ilumina DNA Prep enrichment kit. This kit should enable the preparation of enrichment-based sequencing sufficient for 8 enrichment reactions of 12 samples each, that is, for a total of 96 samples. Illumina Exome Panel – Enrichment Oligos Only, or equivalent.

Наслов на делот: 96 dual indices of size 10 nucleotide bases each with pre-prepared combinations at the i5 and i7 end. This kit is compatible with the Ilumina DNA Prep enrichment kit. Pre-prepared on a 96 position boa
Број на дел: 11
Краток опис:

96 dual indices of size 10 nucleotide bases each with pre-prepared combinations at the i5 and i7 end. This kit is compatible with the Ilumina DNA Prep enrichment kit. Pre-prepared on a 96 position board and ready to use. Each well on the plate should have a unique combination. IDT® for Illumina® DNA/RNA UD Indexes Set A, Tagmentation, or equivalent.

Наслов на делот: Human Whole Exome Sequencing Panel. Panel to include kit of reagents, indexes, library and 96-sample sequencing cartridges with included cartridges for a minimum of 6 analyzes of 16 samples at a time
Број на дел: 12
Краток опис:

Human Whole Exome Sequencing Panel. Panel to include kit of reagents, indexes, library and 96-sample sequencing cartridges with included cartridges for a minimum of 6 analyzes of 16 samples at a time compatible with NextSeq550dx personal sequencer or equivalent

Наслов на делот: Purification solution validated and recommended according to the Nextera Flex library manual purification protocol for the Illumina Miseq personal sequencer, based on the principle of paramagnetic par
Број на дел: 13
Краток опис:

Purification solution validated and recommended according to the Nextera Flex library manual purification protocol for the Illumina Miseq personal sequencer, based on the principle of paramagnetic particles to remove contaminants

Наслов на делот: An oncology panel that includes a complete set of NGS sequencing reagents for at least 24 DNA and/or RNA samples obtained from paraffin-embedded tissues. The panel should enable the detection of at le
Број на дел: 14
Краток опис:

An oncology panel that includes a complete set of NGS sequencing reagents for at least 24 DNA and/or RNA samples obtained from paraffin-embedded tissues. The panel should enable the detection of at least 500 genes from DNA, and at least 50 genes from RNA associated with prognosis and/or prediction of response to therapy in various malignant diseases. The panel should have the ability to add unique molecular identifiers to the DNA fragments that allow simultaneous removal of errors in the detection of low-frequency variants and should have an analytical sensitivity of at least 96% and an analytical specificity of at least 99.9%. The panel should allow the analysis of at least the following genes: NTRK1, NTRK2, NTRK3, BRAF, BRCA 1, BRCA2, TP53, EGFR, KRAS, ALK. The panel should enable the detection of at least the following parameters: Single Nucleotide Variants (SNVs), Multiple Nucleotide Variants (MNV), Copy Number Variants (CNVs), Gene Fusions, Insertions-Deletions (indels), Transcript Variants, detection of microsatellite instability (MSI) and detection of the total number of changes in the DNA of cancer cells (TMB). The panel must include software analysis with clinical interpretation and report and be validated (or compatible?) for the NextSeq550dx personal sequencer or equivalent.

Наслов на делот: NGS sequencing panel of circulating DNA isolated from plasma. The panel allows the analysis of a minimum of 25 targeted genes including EGFR, NRAS, KRAS, ERBB2/HER2, FGFR1, KRAS, BRAF, ESR1, PIK3CA an
Број на дел: 15
Краток опис:

NGS sequencing panel of circulating DNA isolated from plasma. The panel allows the analysis of a minimum of 25 targeted genes including EGFR, NRAS, KRAS, ERBB2/HER2, FGFR1, KRAS, BRAF, ESR1, PIK3CA and NTRK genes. The panel should enable the detection of at least the following parameters: indels, single nucleotide polymorphism (SNP), copy number variation (CNV). The panel should include reagents for library preparation, quantification, specific molecular barcodes (adapters), and software to analyze the data and generate a clinical report that includes annotated variants with approved therapies. The panel should have the ability to add unique molecular identifiers to the DNA fragments that allow for the simultaneous removal of errors in the detection of low-frequency variants and should have an analytical sensitivity of at least 96% and an analytical specificity of at least 99.9% in the detection of high-frequency variants of 0.1%. The panel should allow the sequencing of a minimum of 48 samples at once. The complete panel must be CE-IVD certified and validated for the NextSeq550dx personal sequencer or equivalent.

Постапка
Правна основа: 32014L0024
Време за прием на понуди: 09:00
Јазици на кои може да се поднесат понуди или барања за учество: македонски 🗣️
Период на важност на понудата: 4 месеци
Датум на отворање на понудите: 2022-09-23 📅
Време на отворање на понудите: 09:00
Место: Macedonian Academy of Sciences and Arts

Договорен орган
Идентитет
Национален регистарски број: 4063201
Контакт
URL на документи: https://www.e-nabavki.gov.mk/PublicAccess/home.aspx#/dossie/bd3fc7ce-f8fc-452d-8dfe-309359709971/1 🌏

Дополнителни информации
Тело за преглед
Име: Macedonian Academy of Sciences and Arts
Поштенска адреса: bul. Krste Misirkov br. 2
Поштенско место: Skopje
Поштенски број: 1000
Земја: Северна Македонија 🇲🇰
Е-пошта: manu@manu.edu.mk 📧
Орган од каде што може да се добијат информации за постапката за ревизија
Исто како: Тело за преглед
Извор: OJS 2022/S 165-470179 (2022-08-24)

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Медицинска опрема, фармацевтски производи и производи за лична нега (19 нови набавки)